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-You: The nameless protagonist of the game, more of an observer than an active participant. You find yourself locked up in a prison cell, unaware of your surroundings and confused.

-Salvadore: An avid traveler, Salvadore is your ambiguous best friend who does his best to make your life in prison the best he can with several gifts.

  -Dr. Money: The main antagonist of the story; it is revealed in the beginning of the game he is holding you captive as a "special" program for inmates regarding health and safety.

   -Mr. Smiley: A "happy buddy" hired by Dr. Money intended to keep the protagonist cheerful despite his dreary surroundings.

   -Charlotte: A mysterious woman who is revealed early on to be one of the only other survivors of the rapidly spreading disease. An avid baker, she also owns a pastry shop.